Lentiviral human ROBO1 sgRNA gene knockout kit

Human ROBO1

Gene symbol: ROBO1
Synonyms: DUTT1 SAX3
Species: HUMAN
Gene ID: 6091
Summary: Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_002941:11:10 NM_133631:10:10 NM_001145845:10:10