Lentiviral human RDM1 sgRNA gene knockout kit

Lentiviral human RDM1 sgRNA gene knockout kit

Catalog Number:
CGKK539446FEN
Mfr. No.:
HKO-617658
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human RDM1
          About Target
          Gene symbol: RDM1
          Synonyms: RAD52B
          Species: HUMAN
          Gene ID: 201299
          Summary: This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_145654:3:3 NM_001330194:3:3 NM_001163120:3:3 NM_001163121:3:3 NM_001163122:2:2 NM_001163124:2:2 NM_001163125:2:2 NM_001163130:2:2 NM_001034836:3:3
      • Properties
        • * For Research Use Only.

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