Lentiviral human RBFOX2 sgRNA gene knockout kit

Lentiviral human RBFOX2 sgRNA gene knockout kit

Catalog Number:
CGKK539507FEN
Mfr. No.:
HKO-617597
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human RBFOX2
          About Target
          Gene symbol: RBFOX2
          Synonyms: dJ106I20.3 Fox-2 FOX2 fxh HNRBP2 HRNBP2 RBM9 RTA
          Species: HUMAN
          Gene ID: 23543
          Summary: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001031695:2:2 NM_001349982:3:3 NM_001349983:2:2 NM_001349989:3:3 NM_001349990:3:3 NM_001349991:3:3 NM_001349992:3:3 NM_001349994:3:3 NM_001349995:3:3 NM_001349996:3:3 NM_001349997:2:2 NM_001349998:2:2 NM_001349999:3:3 NM_014309:2:2 NM_001082576:2:2 NM_001082577:2:2 NM_001082578:3:3 NM_001082579:3:3
      • Properties
        • * For Research Use Only.

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