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Overview
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Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers
sgRNA lentiviral particle information
• Functional titer: 1x10^8 TU/ml
• Titration method: counting puromycin resistant cell clones
• Purity: In vivo grade
• Pseudotype: VSVG
• Storage buffer: LentiShield™ lentivirus storage buffer
• Storage: condition -80°C
• Availability: 3-5 weeks
sgRNA lentiviral plasmid information
• Promoter for target sgRNA: U6
• Mammalian selection: puromycin
• Promoter for mammalian selection gene: EF1a
• E.coli selection: Amp
• Storage condition: -20°C
• Availability: 1-2 weeksPlease contact us at for specific academic pricing.
Target Information
Target NameHuman LPPAbout TargetGene symbol: LPP
Synonyms: N/A
Species: HUMAN
Gene ID: 4026
Summary: This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_005578:4:2 NM_001167671:5:2 NM_001167672:3:2 NM_001375455:4:2 NM_001375456:4:2 NM_001375457:5:2 NM_001375461:4:2 NM_001375458:4:2 NM_001375459:4:2 NM_001375460:5:2 NM_001375462:5:2 NM_001375463:4:2 NM_001375465:3:2 NM_001375464:5:2
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- Properties
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Overview