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Overview
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Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers
sgRNA lentiviral particle information
• Functional titer: 1x10^8 TU/ml
• Titration method: counting puromycin resistant cell clones
• Purity: In vivo grade
• Pseudotype: VSVG
• Storage buffer: LentiShield™ lentivirus storage buffer
• Storage: condition -80°C
• Availability: 3-5 weeks
sgRNA lentiviral plasmid information
• Promoter for target sgRNA: U6
• Mammalian selection: puromycin
• Promoter for mammalian selection gene: EF1a
• E.coli selection: Amp
• Storage condition: -20°C
• Availability: 1-2 weeksPlease contact us at for specific academic pricing.
Target Information
Target NameHuman LPAR1About TargetGene symbol: LPAR1
Synonyms: edg-2 EDG2 Gpcr26 GPR26 LPA1 Mrec1.3 rec.1.3 vzg-1 VZG1
Species: HUMAN
Gene ID: 1902
Summary: The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001401:3:2 NM_001351397:4:2 NM_001351398:6:2 NM_001351399:5:2 NM_001351400:6:2 NM_001351401:6:2 NM_001351402:5:2 NM_001351403:4:2 NM_001351404:5:2 NM_001351405:5:2 NM_001351406:4:2 NM_001351407:6:2 NM_001351408:5:2 NM_001351409:6:2 NM_001351410:6:2 NM_001351411:5:2 NM_001351412:6:2 NM_001351413:6:2 NM_001351414:5:2 NM_001351415:6:2 NM_001351416:5:2 NM_001351417:5:2 NM_001351418:6:2 NM_001351419:5:2 NM_001351420:5:2 NM_057159:4:2
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- Properties
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Overview