Lentiviral human LONP2 sgRNA gene knockout kit

Human LONP2

Gene symbol: LONP2
Synonyms: LONP LONPL PLON PSLON
Species: HUMAN
Gene ID: 83752
Summary: In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_031490:7:7