Lentiviral human LMX1B sgRNA gene knockout kit

Human LMX1B

Gene symbol: LMX1B
Synonyms: LMX1.2 NPS1
Species: HUMAN
Gene ID: 4010
Summary: This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_002316:3:3