Lentiviral human KMT2B sgRNA gene knockout kit

Human KMT2B

Gene symbol: KMT2B
Synonyms: CXXC10 DYT28 HRX2 MLL1B MLL2 MLL4 TRX2 WBP-7 WBP7
Species: HUMAN
Gene ID: 9757
Summary: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_014727:3:3