Lentiviral human KIRREL3 sgRNA gene knockout kit

Human KIRREL3

Gene symbol: KIRREL3
Synonyms: KIRRE MRD4 NEPH2 PRO4502
Species: HUMAN
Gene ID: 84623
Summary: The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_032531:3:3 NM_001161707:3:3 NM_001301097:3:3