Lentiviral human KCNQ5 sgRNA gene knockout kit

Lentiviral human KCNQ5 sgRNA gene knockout kit

Catalog Number:
CGKK542563FEN
Mfr. No.:
HKO-614533
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human KCNQ5
          About Target
          Gene symbol: KCNQ5
          Synonyms: Kv7.5 MRD46
          Species: HUMAN
          Gene ID: 56479
          Summary: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_019842:5:5 NM_001160130:5:5 NM_001160132:5:5 NM_001160133:5:5 NM_001160134:5:5
      • Properties
        • * For Research Use Only.

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