Lentiviral human KCNMB3 sgRNA gene knockout kit

Lentiviral human KCNMB3 sgRNA gene knockout kit

Catalog Number:
CGKK542569FEN
Mfr. No.:
HKO-614527
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human KCNMB3
          About Target
          Gene symbol: KCNMB3
          Synonyms: BKBETA3 HBETA3 K(VCA)BETA-3 KCNMB2 KCNMBL SLO-BETA-3 SLOBETA3
          Species: HUMAN
          Gene ID: 27094
          Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_171828:3:3 NM_171829:3:3 NM_171830:2:2 NM_014407:3:3 NM_001163677:3:3
      • Properties
        • * For Research Use Only.

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