Lentiviral human KCNJ2 sgRNA gene knockout kit

Human KCNJ2

Gene symbol: KCNJ2
Synonyms: ATFB9 HHBIRK1 HHIRK1 IRK1 KIR2.1 LQT7 SQT3
Species: HUMAN
Gene ID: 3759
Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000891:2:1