Lentiviral human KCNE2 sgRNA gene knockout kit

Human KCNE2

Gene symbol: KCNE2
Synonyms: ATFB4 LQT5 LQT6 MIRP1
Species: HUMAN
Gene ID: 9992
Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_172201:2:1