Lentiviral human KAT6B sgRNA gene knockout kit

Human KAT6B

Gene symbol: KAT6B
Synonyms: GTPTS MORF MOZ2 MYST4 qkf querkopf ZC2HC6B
Species: HUMAN
Gene ID: 23522
Summary: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_012330:14:12