Lentiviral human IRF6 sgRNA gene knockout kit

Human IRF6

Gene symbol: IRF6
Synonyms: LPS OFC6 PIT PPS PPS1 VWS VWS1
Species: HUMAN
Gene ID: 3664
Summary: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_006147:7:5 NM_001206696:5:4