Lentiviral human INTS11 sgRNA gene knockout kit

Lentiviral human INTS11 sgRNA gene knockout kit

Catalog Number:
CGKK543003FEN
Mfr. No.:
HKO-614307
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human INTS11
          About Target
          Gene symbol: INTS11
          Synonyms: CPSF3L CPSF73L INT11 RC-68 RC68
          Species: HUMAN
          Gene ID: 54973
          Summary: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001256456:11:9 NM_017871:9:9 NM_001256460:10:8 NM_001256462:7:7 NM_001256463:7:7
      • Properties
        • * For Research Use Only.

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