Lentiviral human ILF3 sgRNA gene knockout kit

Human ILF3

Gene symbol: ILF3
Synonyms: CBTF DRBF DRBP76 MMP4 MPHOSPH4 MPP4 MPP4110 NF-AT-90 NF110 NF110b NF90 NF90a NF90b NF90c NF90ctv NFAR NFAR-1 NFAR-2 NFAR110 NFAR2 NFAR90 TCP110 TCP80
Species: HUMAN
Gene ID: 3609
Summary: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_012218:13:12 NM_017620:13:12 NM_001137673:13:12 NM_153464:13:12 NM_004516:13:12