Lentiviral human IL21 sgRNA gene knockout kit

Human IL21

Gene symbol: IL21
Synonyms: CVID11 IL-21 Za11
Species: HUMAN
Gene ID: 59067
Summary: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_021803:1:1 NM_001207006:1:1