Lentiviral human IHH sgRNA gene knockout kit

Human IHH

Gene symbol: IHH
Synonyms: BDA1 HHG2
Species: HUMAN
Gene ID: 3549
Summary: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_002181:3:3