Lentiviral human IGF2 sgRNA gene knockout kit

Human IGF2

Gene symbol: IGF2
Synonyms: C11orf43 GRDF IGF-II PP9974
Species: HUMAN
Gene ID: 3481
Summary: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000612:3:2 NM_001007139:4:2 NM_001127598:4:3 NM_001291861:3:2 NM_001291862:3:2