Lentiviral human IFT122 sgRNA gene knockout kit

Human IFT122

Gene symbol: IFT122
Synonyms: CED CED1 SPG WDR10 WDR10p WDR140
Species: HUMAN
Gene ID: 55764
Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_052985:13:13