Lentiviral human IFI16 sgRNA gene knockout kit

Human IFI16

Gene symbol: IFI16
Synonyms: IFNGIP1 PYHIN2
Species: HUMAN
Gene ID: 3428
Summary: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001206567:6:5 NM_005531:7:6 NM_001364867:8:6 NM_001376587:7:6 NM_001376588:8:6 NM_001376589:8:6 NM_001376591:8:6 NM_001376592:7:6