Lentiviral human HTRA4 sgRNA gene knockout kit

Human HTRA4

Gene symbol: HTRA4
Synonyms: N/A
Species: HUMAN
Gene ID: 203100
Summary: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_153692:1:1