Lentiviral human HSD17B10 sgRNA gene knockout kit

Human HSD17B10

Gene symbol: HSD17B10
Synonyms: 17b-HSD10 ABAD CAMR DUPXp11.22 ERAB HADH2 HCD2 HSD10MD MHBD MRPP2 MRX17 MRX31 MRXS10 SCHAD SDR5C1
Species: HUMAN
Gene ID: 3028
Summary: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004493:2:2 NM_001037811:2:2