Lentiviral human HOMER3 sgRNA gene knockout kit

Human HOMER3

Gene symbol: HOMER3
Synonyms: HOMER-3 VESL3
Species: HUMAN
Gene ID: 9454
Summary: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001145722:3:2 NM_001145721:3:2 NM_001145724:2:2 NM_004838:3:2