Lentiviral human HLCS sgRNA gene knockout kit

Lentiviral human HLCS sgRNA gene knockout kit

Catalog Number:
CGKK543345FEN
Mfr. No.:
HKO-613965
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

          Please contact us at for specific academic pricing.

          Target Information

          Target Name
          Human HLCS
          About Target
          Gene symbol: HLCS
          Synonyms: HCS
          Species: HUMAN
          Gene ID: 3141
          Summary: This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000411:5:2 NM_001242785:5:2 NM_001242784:5:2 NM_001352514:4:4 NM_001352515:4:2 NM_001352516:4:2 NM_001352517:4:2 NM_001352518:4:2
      • Properties
        • * For Research Use Only.

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