Lentiviral human HDAC9 sgRNA gene knockout kit

Lentiviral human HDAC9 sgRNA gene knockout kit

Catalog Number:
CGKK543430FEN
Mfr. No.:
HKO-613880
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human HDAC9
          About Target
          Gene symbol: HDAC9
          Synonyms: HD7 HD7b HD9 HDAC HDAC7 HDAC7B HDAC9B HDAC9FL HDRP MITR
          Species: HUMAN
          Gene ID: 9734
          Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_058176:10:10 NM_014707:11:10 NM_178423:11:10 NM_178425:10:10 NM_001204144:12:11 NM_001204145:10:9 NM_001204146:10:9 NM_001204147:9:8 NM_001204148:10:9 NM_001321868:11:10 NM_001321869:12:11 NM_001321870:12:11 NM_001321871:11:10 NM_001321872:11:10 NM_001321873:11:10 NM_001321874:11:10 NM_001321875:11:10 NM_001321876:11:10 NM_001321877:10:9 NM_001321878:11:10 NM_001321879:10:9 NM_001321884:11:10 NM_001321885:10:9 NM_001321886:12:9 NM_001321887:12:9 NM_001321888:10:9 NM_001321889:11:8 NM_001321890:11:10 NM_001321891:10:9 NM_001321893:11:9 NM_001321894:11:9 NM_001321895:10:9 NM_001321896:12:9 NM_001321897:11:9 NM_001321898:10:9 NM_001321899:12:10 NM_001321900:11:10 NM_001321901:11:10 NM_001321902:11:10
      • Properties
        • * For Research Use Only.

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