Lentiviral human GSR sgRNA gene knockout kit

Human GSR

Gene symbol: GSR
Synonyms: GR GSRD HEL-75 HEL-S-122m
Species: HUMAN
Gene ID: 2936
Summary: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000637:5:5 NM_001195102:5:5 NM_001195103:5:5 NM_001195104:5:5