Lentiviral human GRM5 sgRNA gene knockout kit

Human GRM5

Gene symbol: GRM5
Synonyms: GPRC1E mGlu5 MGLUR5 PPP1R86
Species: HUMAN
Gene ID: 2915
Summary: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001143831:7:7 NM_000842:8:7