Lentiviral human GRIK1 sgRNA gene knockout kit

Human GRIK1

Gene symbol: GRIK1
Synonyms: EAA3 EEA3 GLR5 GluK1 gluR-5 GLUR5
Species: HUMAN
Gene ID: 2897
Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000830:7:7 NM_175611:7:7 NM_001320616:7:7 NM_001320618:6:6 NM_001320621:5:5 NM_001320630:7:7 NM_001330993:7:7 NM_001330994:7:7