Lentiviral human GRIA1 sgRNA gene knockout kit

Lentiviral human GRIA1 sgRNA gene knockout kit

Catalog Number:
CGKK543597FEN
Mfr. No.:
HKO-613713
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human GRIA1
          About Target
          Gene symbol: GRIA1
          Synonyms: GluA1 GLUH1 GLUR1 GLURA HBGR1
          Species: HUMAN
          Gene ID: 2890
          Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000827:6:6 NM_001114183:6:6 NM_001258019:5:5 NM_001258020:7:4 NM_001258021:6:6 NM_001258022:6:6 NM_001258023:6:5 NM_001364165:6:6 NM_001364166:7:7 NM_001364167:6:5
      • Properties
        • * For Research Use Only.

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