Lentiviral human GRAP2 sgRNA gene knockout kit

Lentiviral human GRAP2 sgRNA gene knockout kit

Catalog Number:
CGKK543608FEN
Mfr. No.:
HKO-613702
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human GRAP2
          About Target
          Gene symbol: GRAP2
          Synonyms: GADS GRAP-2 GRB2L GRBLG GrbX Grf40 GRID GRPL Mona P38
          Species: HUMAN
          Gene ID: 9402
          Summary: This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001291824:6:5 NM_001291825:5:5 NM_001291826:5:3 NM_001291828:3:2 NM_004810:6:5
      • Properties
        • * For Research Use Only.

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