Lentiviral human GPD1 sgRNA gene knockout kit

Human GPD1

Gene symbol: GPD1
Synonyms: GPD-C GPDH-C HTGTI
Species: HUMAN
Gene ID: 2819
Summary: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_005276:2:2 NM_001257199:2:2