Lentiviral human GLIS3 sgRNA gene knockout kit

Human GLIS3

Gene symbol: GLIS3
Synonyms: NDH ZNF515
Species: HUMAN
Gene ID: 169792
Summary: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001042413:4:3 NM_152629:3:2