Lentiviral human GFM1 sgRNA gene knockout kit

Lentiviral human GFM1 sgRNA gene knockout kit

Catalog Number:
CGKK543846FEN
Mfr. No.:
HKO-613464
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human GFM1
          About Target
          Gene symbol: GFM1
          Synonyms: COXPD1 EFG EFG1 EFGM EGF1 GFM hEFG1 mtEF-G1
          Species: HUMAN
          Gene ID: 85476
          Summary: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001308164:8:8 NM_001308166:7:7 NM_024996:7:7 NM_001374355:8:8 NM_001374356:6:6 NM_001374357:7:6 NM_001374358:4:4 NM_001374359:5:4 NM_001374360:5:4 NM_001374361:4:3
      • Properties
        • * For Research Use Only.

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