Lentiviral human GAD2 sgRNA gene knockout kit

Human GAD2

Gene symbol: GAD2
Synonyms: GAD65
Species: HUMAN
Gene ID: 2572
Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_000818:4:4 NM_001134366:4:4