Lentiviral human GABBR2 sgRNA gene knockout kit

Human GABBR2

Gene symbol: GABBR2
Synonyms: EIEE59 GABABR2 GPR51 GPRC3B HG20 HRIHFB2099 NDPLHS
Species: HUMAN
Gene ID: 9568
Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_005458:6:6