Lentiviral human FBXO31 sgRNA gene knockout kit

Human FBXO31

Gene symbol: FBXO31
Synonyms: FBX14 Fbx31 FBXO14 MRT45 pp2386
Species: HUMAN
Gene ID: 79791
Summary: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_024735:7:7 NM_001282683:8:4