Lentiviral human FBXL2 sgRNA gene knockout kit

Human FBXL2

Gene symbol: FBXL2
Synonyms: FBL2 FBL3
Species: HUMAN
Gene ID: 25827
Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_012157:10:10 NM_001349316:10:10 NM_001349319:10:5 NM_001349320:10:5 NM_001349321:11:5 NM_001349322:8:6 NM_001349323:10:5 NM_001349324:10:5 NM_001349325:11:5 NM_001349326:12:5