Lentiviral human FADS2 sgRNA gene knockout kit

Lentiviral human FADS2 sgRNA gene knockout kit

Catalog Number:
CGKK544374FEN
Mfr. No.:
HKO-612936
Price:
$878
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      • Overview
        • Kit Components: Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

          sgRNA lentiviral particle information
          • Functional titer: 1x10^8 TU/ml
          • Titration method: counting puromycin resistant cell clones
          • Purity: In vivo grade
          • Pseudotype: VSVG
          • Storage buffer: LentiShield™ lentivirus storage buffer
          • Storage: condition -80°C
          • Availability: 3-5 weeks

          sgRNA lentiviral plasmid information
          • Promoter for target sgRNA: U6
          • Mammalian selection: puromycin
          • Promoter for mammalian selection gene: EF1a
          • E.coli selection: Amp
          • Storage condition: -20°C
          • Availability: 1-2 weeks

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          Target Information

          Target Name
          Human FADS2
          About Target
          Gene symbol: FADS2
          Synonyms: D6D DES6 FADSD6 LLCDL2 SLL0262 TU13
          Species: HUMAN
          Gene ID: 9415
          Summary: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
          NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004265:3:3 NM_001281501:3:3 NM_001281502:3:3
      • Properties
        • * For Research Use Only.

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