Lentiviral human ERVFRD-1 sgRNA gene knockout kit

Human ERVFRD-1

Gene symbol: ERVFRD-1
Synonyms: envFRD ERVFRDE1 GLLL6191 HERV-FRD HERV-W/FRD UNQ6191
Species: HUMAN
Gene ID: 405754
Summary: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Jun 2012].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_207582:2:1