Lentiviral human EOMES sgRNA gene knockout kit

Human EOMES

Gene symbol: EOMES
Synonyms: TBR2
Species: HUMAN
Gene ID: 8320
Summary: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001278182:3:3