Lentiviral human EGFR sgRNA gene knockout kit

Human EGFR

Gene symbol: EGFR
Synonyms: ERBB ERBB1 HER1 mENA NISBD2 PIG61
Species: HUMAN
Gene ID: 1956
Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001346941:2:2 NM_005228:8:8 NM_201282:8:8 NM_201283:8:8 NM_201284:8:8 NM_001346897:7:7 NM_001346898:8:8 NM_001346899:7:7 NM_001346900:8:7