Lentiviral human DYRK3 sgRNA gene knockout kit

Human DYRK3

Gene symbol: DYRK3
Synonyms: DYRK5 hYAK3-2 RED REDK
Species: HUMAN
Gene ID: 8444
Summary: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_003582:3:3