Lentiviral human DUSP19 sgRNA gene knockout kit

Human DUSP19

Gene symbol: DUSP19
Synonyms: DUSP17 LMWDSP3 SKRP1 TS-DSP1
Species: HUMAN
Gene ID: 142679
Summary: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_080876:1:1 NM_001142314:1:1 NM_001321519:1:1