Lentiviral human DNM1 sgRNA gene knockout kit

Human DNM1

Gene symbol: DNM1
Synonyms: DNM EIEE31
Species: HUMAN
Gene ID: 1759
Summary: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_004408:3:3 NM_001005336:3:3 NM_001288737:3:3 NM_001288738:3:3 NM_001288739:3:3 NM_001374269:3:3