Lentiviral human DHX16 sgRNA gene knockout kit

Human DHX16

Gene symbol: DHX16
Synonyms: DBP2 DDX16 PRO2014 Prp2 PRP8 PRPF2
Species: HUMAN
Gene ID: 8449
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_003587:10:10 NM_001164239:10:10 NM_001363515:11:2