Lentiviral human DGKB sgRNA gene knockout kit

Human DGKB

Gene symbol: DGKB
Synonyms: DAGK2 DGK DGK-BETA
Species: HUMAN
Gene ID: 1607
Summary: Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001350705:9:8 NM_145695:8:8 NM_001350706:9:8 NM_001350707:9:8 NM_001350708:9:8 NM_001350709:9:8 NM_001350711:8:7 NM_001350712:8:7 NM_001350714:8:7 NM_001350715:8:7 NM_001350716:8:7 NM_001350717:9:8 NM_001350718:9:8 NM_001350719:9:8 NM_001350720:8:7 NM_001350721:8:7 NM_001350722:9:7 NM_001350723:9:7 NM_001350724:8:6