Lentiviral human DDX5 sgRNA gene knockout kit

Human DDX5

Gene symbol: DDX5
Synonyms: G17P1 HLR1 HUMP68 p68
Species: HUMAN
Gene ID: 1655
Summary: This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001320595:7:6 NM_004396:6:6 NM_001320596:7:6 NM_001320597:6:6