Lentiviral human DDR1 sgRNA gene knockout kit

Human DDR1

Gene symbol: DDR1
Synonyms: CAK CD167 DDR EDDR1 HGK2 MCK10 NEP NTRK4 PTK3 PTK3A RTK6 TRKE
Species: HUMAN
Gene ID: 780
Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001954:10:7 NM_013993:9:7 NM_013994:7:7 NM_001202521:7:7 NM_001202522:7:7 NM_001202523:8:8 NM_001297652:8:7 NM_001297653:8:7 NM_001297654:8:7